New Covid variant 'IHU' identified in France, has 46 mutations

As the world grapples with the highly mutated Omicron variant of SARS-CoV-2, a new variant has emerged in France.The new strain has been identified by scientists in Southern France. Known as 'IHU', the B.1.640.2 variant is said to have 46 mutations, as per a study that is yet to be peer-reviewed. The variant has not been identified in other countries so far or labeled a variant under investigation by the World Health Organization (WHO). According to researchers, the first case of the IHU variant was found in a sample whose RT-PCR test was done in November last year.

The variant has been reported by researchers at institute IHU Mediterranee Infection in at least 12 cases, and has been linked to travel to African country Cameroon. However, the researchers noted that it is too early to speculate on how this variant behaves as far as infection and protection from vaccines are concerned. Apart from 46 mutations, the study released on December 29 also revealed that IHU has 37 deletions resulting in 30 amino acid substitutions and 12 deletions. Amino acids are molecules that combine to form proteins, and both are the building blocks of life. Fourteen amino acid substitutions, including N501Y and E484K, and nine deletions are located in the spike protein.

"The mutation set and phylogenetic position of the genomes obtained here indicate based on our previous definition a new variant we named IHU," the authors of the study said. Epidemiologist Eric Feigl-Ding posted a long Twitter thread in which he said that new variants keep emerging but it does not necessarily mean they will be more dangerous.